6 warning signs of multiple myeloma

6 warning signs of multiple myeloma

Multiple myeloma is a type of cancer affecting the plasma cells in the bone marrow, which form an essential part of the immune system. While there is no cure for the disorder, many treatments help control and manage the symptoms so patients can maintain their quality of life. Read on to learn about a few early signs of multiple myeloma that can help diagnose the condition and seek appropriate treatment.

Multiple myeloma – Signs to look out for
Multiple myeloma is difficult to diagnose in the early stages. It is usually identified much later because patients do not show signs initially. Some may report vague symptoms that appear to have been caused by other conditions. Still, it is crucial to know the signs that could indicate a possibility of multiple myeloma. Those who experience the following should visit a doctor as soon as possible and undergo the necessary tests to rule out the condition:

Bone pain
One of the most common signs of multiple myeloma is bone pain. Those with this disorder may notice pain in the back, ribs, and hips. It can be consistent and dull and worsen with movement. The pain is usually a result of the multiplication of cancerous plasma cells in the bone marrow.

Fractures
Multiple myeloma can cause the bones in the body to become weak and brittle, making them prone to fractures. Typically, the weakening is noticed in the spine and long bones, such as those in the arms and legs. Fractures may cause the spine to collapse, leading to unbearable pain and difficulty moving. Brittle bones can also lead to secondary bone diseases, such as osteoporosis. Osteoporosis can affect all the bones in the body or specific areas.

Spine compression
Those with multiple myeloma may also experience spinal cord compression, which could lead to secondary symptoms. These include a sensation of pins and needles pricking the body, numbness in the legs, and trouble controlling the bladder.

Constant infections
Multiple myeloma patients are more prone to infections. The abnormal cancer cells in the bone start to outgrow and crowd out the healthy blood cells. Also, the cancerous cells make abnormal proteins instead of producing antibodies for the immune system to fight infections. This leads to severe complications and constant and repeated infections.

Increased calcium levels
The disorder can lead to increased levels of calcium in the body, also known as hypercalcemia. It happens when the affected bones break down and become brittle, releasing calcium into the blood. Symptoms of increased calcium levels include extreme thirst, constipation, confusion, pain in the stomach, and frequent need to urinate.

Anemia
Those with multiple myeloma are also prone to anemia, characterized by a lack of or low amounts of red blood cells in the bloodstream. Anemia occurs because the condition affects the production of these blood cells in the bone marrow. Those with anemia may feel tired, dizzy, breathless, and weak. It could be an early sign of multiple myeloma if these discomforts persist and do not go away.

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Hyperkalemia – 10 foods to avoid

Potassium plays a huge role in the health of our heart muscles and nerve cells. And high levels of this element in the blood cause hyperkalemia. If you consume meals high in potassium, your doctor may advise you to decrease portion sizes and concentrate on fruits and vegetables with a lower potassium content. Here is a list of foods rich in potassium that must be avoided if you have hyperkalemia. Yogurt and dairy products A serving of nonfat yogurt weighing eight ounces has roughly 625 mg of potassium, making it one of the dairy aisle's highest sources of potassium. Even reduced fat milk contains 366 mg of potassium in a glass of cow's whole milk. Ricotta and cottage cheese are also high in potassium. Goat cheese is a low potassium food, proving that not all cheeses are made equal. Likewise, About 131 milligrams of potassium may be found in a half cup of vanilla ice cream. Bananas When people consider foods high in potassium, bananas frequently come to mind. A banana normally contains 422 mg of potassium. Among all the fruit, bananas are athletes' favorite as they provide energy. However, it could be highly dangerous for someone suffering from hyperkalemia. Consult your doctor if you have hyperkalemia and stick to fruits such as apples and berries. Leafy vegetables About 420 milligrams of potassium can be found in only a half cup of cooked spinach. Raw spinach, young or mature, has roughly 167 mg per cup. Fennel, bok choy, beet greens, and Swiss chard are also high in potassium. You can opt for kale instead. Kale has more nutrients than these other dark leafy greens, but it has less potassium. 73 mg is present in one cup of raw kale. Fish Clams, which provide 534 mg of potassium in just 3 ounces, are the finest source of protein from seafood. Around three ounces of skipjack tuna offers 444 mg, another major source of potassium. One of the most popular fish, salmon, frequently has a lower potassium content. Keeping a check on what type of fish you are eating if you have hyperkalemia is a must. Kidney beans Beans are a balanced addition to any meal plan as they're rich sources of protein and fiber. However, according to data from the USDA, one cup of the kidney-shaped type has 713 mg of potassium. A half-cup of black beans has 489 mg of potassium. Avocado This creamy, green-fleshed fruit is packed with 690 mg of potassium and is high in fiber and heart-healthy lipids. Although it might seem good for your heart, you should avoid it if you have hyperkalemia. Potatoes Potassium is heavily concentrated in potatoes; 925 milligrams of potassium may be found in a baked potato. A three-ounce portion of french-fried potatoes has 470 mg of potassium and a lot of fat and calories. The potassium content in an ounce of potato chips is 465 mg. Indulging in fast foods like fries is adverse for those with hyperkalemia. Oranges A single orange has 240 mg of potassium, making it a food with a high potassium content. With 450 mg per 8 oz glass, orange juice is a more potent source of potassium. Fruits vary in their potassium content. Berries are a poor source of potassium and can be a decent substitute for oranges and orange juice. Another good option is apples. Dried fruits The nutrients in fruit, including potassium, that have been dried are concentrated. You get roughly 750 milligrams from half a cup of dried apricots. Also, even though raisins and dried plums make a fantastic snack, they should be avoided by someone with hyperkalemia. Legumes and beans Legumes are a significant source of potassium as well. White beans have the most, with 600 mg of potassium in a half cup. In half a cup serving, other legumes such as lima beans and pinto beans have between 300 and 350 mg.

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7 foods that help reduce the risk of cancer

In a world where most ready-to-eat meals contain excess fats and calories, finding a balance becomes necessary. The food one consumes helps maintain overall health, reduces the risk of a disease, and hastens the recovery process. This is particularly true in the case of cancer. While no food can cure cancer, intake of certain vegetables, such as the ones given below, may reduce its risk. This article additionally touches upon options for cancer treatment. 7 Foods That Help Reduce the Risk of Cancer Berries Berries like blackberries, mulberries, strawberries, and blueberries are rich sources of vitamin C, folate, potassium, and manganese. They also contain a high amount of antioxidants, including ellagic acid, gallic acid, and chlorogenic acid, and have anti-cancer properties. Garlic Garlic is a vegetable that contains an active compound called allicin. One study concluded that people who ate a large number of allicin-rich vegetables such as garlic, onions, leeks, and shallots had a lower risk of stomach cancer. Tomato According to some experts, this fruit is a cancer-fighting superfood. Tomatoes contain lycopene, which is an antioxidant phytochemical that keeps away heart diseases. They are, additionally, a rich source of vitamin A, C, and E, all nutrients that help reduce the risk of cancer. Grapes Grapes and other citrus fruits such as lemons, limes, and oranges decrease the risk of cancer, especially of the digestive and upper respiratory tract. They are also known to reduce the risk of pancreatic and stomach cancer. Broccoli Broccoli and other cruciferous vegetables are known for having potent anti-cancer properties. They contain glucosinolates, which produce protective enzymes when they pass through the digestive system. These enzymes help the body to detoxify harmful chemicals that could lower cancer risk. Apples Each slice of an apple contains a high amount of fiber, potassium, and vitamin C. These are beneficial in cancer and its recovery. Apples also contain potassium, which helps prevent fluid retention, a common side effect of chemotherapy. Carrots Carrots are full of vitamin A, vitamin K, and calcium. They are a good source of beta-carotene, an antioxidant that shields cell membranes from toxin damage. Plus, carrots are believed to slow the growth of cancer cells. Treatment Options for Cancer Several studies are ongoing to find the right treatment for every type of cancer. Ibrutinib is one such medicine that is used to treat mantle cell lymphoma, marginal zone lymphoma, Waldenström's macroglobulinemia, chronic lymphocytic leukemia, and small lymphocytic lymphoma. It works by blocking the growth of abnormal protein that leads to the multiplication of cancer cells. Flax seeds are believed to contain potent cancer-fighting compounds like alpha-linoleic acid (ALA), lignans, and phytoestrogens. Studies indicate these compounds improve survival rates among some patients by stopping certain tumors from spreading and causing cell damage. The ALA also helps counter inflammation linked to the progression of many cancers. Also, cancer screenings are a crucial part of the treatment to manage the progression of the disease. Doctors generally suggest sensitive screening tests like a colonoscopy for colon cancer. A colonoscopy provides a complete view of the rectum allowing proctologists and oncologists to identify the extent of the spread depending on the cancer stage. Alternatively, for breast cancer, doctors suggest BRCA gene testing analysis to identify any harmful changes in mutations linked to the progression of breast cancer. Xofigo® is an injectable treatment option for prostate cancer patients. It is used for patients in advanced stages of the condition and those who fail to respond positively to traditional treatment options like surgery or hormonal treatment. Xofigo® radium 223 cancer treatment works because of the radioactive compound radium 223, which plays the role of a radiotherapeutic agent that destroys cancer cells. It can only be used when cancer has spread to the bones of the patient and nowhere else. A healthcare professional can administer the injection, and it is generally injected once every four weeks in six doses. Another cancer treatment method is the chimeric antigen receptor (CAR) T-cell therapy. It is a method wherein the immune cells are genetically modified in a lab so they can attack the cancer cells. Carfilzomib is another medicine used to reduce or completely stop the growth of cancer cells. It is used for treating patients with relapsed or refractory multiple myeloma. Carfilzomib can be used alone or in a combination with daratumumab and dexamethasone; lenalidomide and dexamethasone; or only with dexamethasone. It is available in powder form that is to be mixed with liquid and injected intravenously. It is typically administered over a period of 10 to 30 minutes. This medication may be given for two consecutive days every week for a period of three weeks, or it can be administered once a week over a period of three weeks. Multiple myeloma is a type of cancer that develops in plasma cells—white blood cells that fight infections by making antibodies. While the condition has no cure, a novel course called B-cell maturation antigen (BCMA) is receiving attention. BCMA is a protein that promotes B-cell survival, which helps inhibit cancerous growth. Doctors are in the process of developing therapies and treatments to target the BCMA protein for managing multiple myeloma. Fostamatinib, a spleen tyrosine kinase inhibitor, manages chronic immune thrombocytopenia. It is being investigated for  Immune Thrombocytopenic Purpura (ITP) as well. It is currently sold under brand name Tavalisse® and works by increasing blood platelets. This inhibitor is given after other treatments have failed. Patients should take Tavalisse® as prescribed by the doctor. Potential side effects include high blood pressure, liver problems, diarrhea, and infections. It is believed that messenger RNA, or mRNA, could be the next frontier as a more effective cancer therapy. mRNA carries specific signals to the cells, specifically dendritic cells, that instruct them into producing proteins and strengthening the immune system to kill the invading host cells, such as cancer cells. Numerous clinical trials have been carried out to treat pancreatic, colorectal, and melanoma cancer through this form of immunotherapy. The human body naturally produces antibodies to fight off disease-causing organisms. Monoclonal antibodies are biological antibodies that are prepared in labs and often used as a targeted therapy for cancer patients. They are marked to target specific cells in the body, minimizing harm to healthy cells. These lab-produced monoclonal antibodies mimic the immune system’s response to unwanted cells and destroy them by blocking their growth, destroying cell membranes, flagging cancer cells, and attacking them. XTANDI (enzalutamide) is a recommended novel hormone therapy for prostate cancer. It is used for treating three types of advanced prostate cancer: metastatic castration-sensitive prostate cancer (mCSPC), non-metastatic castration-resistant prostate cancer (nmCRPC), and metastatic castration-resistant prostate cancer (mCRPC). XTANDI is an FDA-approved treatment option and is used orally once daily in either four 40 mg or two 80 mg dosages. It can be had with or without food. Genetic testing can be used to ascertain cancer presence if one is genetically predisposed to the condition or has undergone cancer treatment at a younger age. It helps assess the gene mutation in the body. A healthcare expert tests an individual's DNA by collecting cells at a clinic or from the individual's home. The sample helps identify the signs of cancer development and draw an adequate treatment plan.

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